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Bio Yield Engine - Every bioreactor, Every parameter, in Real Time.

Bio Yield Engine turns your historian into a live control room: per-batch trends for pH, DO, temperature, feed and off-gas, automatic design-space excursion flagging, a feed-strategy optimizer grounded in your own batch history, and Part 11-ready records on demand.

8
sensor channels streamed per batch
< 2 s
historian-to-trend latency
100%
of events captured in the audit trail

How it works

Four steps from raw tags to a defensible batch record. Most teams are watching live trends the same week they connect.

  1. STEP 01

    Connect your historian

    Point Bio Yield Engine at OSIsoft PI, Ignition, DeltaV or your LIMS. Tags map to standard bioprocess channels in minutes — no rip-and-replace.

  2. STEP 02

    Watch every batch live

    pH, DO, temperature, agitation, feed rate, OD and off-gas stream into per-batch trends with design-space bands and automatic excursion flags.

  3. STEP 03

    Act on model-driven guidance

    Regression and growth-curve fits across your batch history suggest feed-rate, induction-timing and setpoint adjustments before yield is lost.

  4. STEP 04

    Export audit-ready records

    Every annotation and deviation lands in a tamper-evident audit trail. Export eBR and CSV batch records built for 21 CFR Part 11 review.

Trusted on the floor

We caught a DO excursion on a pilot run 40 minutes before it would have hit the batch record. That single save paid for the year.
Dr. Priya Raghunathan
Head of Upstream Process Development, Nyra Bio
Batch record assembly used to take our team three days per campaign. Bio Yield Engine exports it in one click and QA stopped chasing signatures.
Marcus Feld
Quality Systems Manager, Halden Therapeutics
The feed optimizer suggested shifting induction two hours later. Titer went up 11% and the reasoning was legible enough to defend in review.
Ana Cardoso
Principal Scientist, Fermentation, Corvia Labs

Frequently asked questions

See your next batch the way it deserves to be seen.

No login, no sales gate — the full bioprocess control module is open. Bring a batch question and see what the trends say.

  • Open access
  • No account required
  • Works with your historian